Search results for " Genome Editing"

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Proposal of a Genome Editing System for Genetic Resistance to Tomato Spotted Wilt Virus

2014

Viruses provoke considerable economical losses in agriculture. New molecular approaches to develop genetic resistance based on translational genomics and precision genetic modifications are highly expected. The type II Clustered, Regularly Interspaced Palindromic Repeats (CRISPR) system including Cas9 nuclease represent a promising and very powerful tool to specifically modulate the expression and activity of genes involved in biotic stress responses. In this study, we describe an approach to develop a platform system based on CRISPR system for genome editing technology in tomato. Tomato is an excellent plant for this approach considering the high-quality genome sequence, the rapid life cyc…

GeneticsWhole genome sequencingMultidisciplinaryCas9fungifood and beveragesBiologyBiotic stressCRISPR-Cas9 Genetic Resistance Genome Editing Plants Tomato TSWVGenomeTransformation (genetics)Genome editingSettore AGR/07 - Genetica AgrariaSettore AGR/01 - Economia Ed Estimo RuraleSettore AGR/08 - Idraulica Agraria E Sistemazioni Idraulico-ForestaliCRISPRGeneAmerican Journal of Applied Sciences

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PEPhysical Sciences and Engineering
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LSLife Sciences
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SHSocial Sciences and Humanities
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